49ers 2025 Season. Take a look at the 49ers' schedule and opponents for the upcoming 2025 season. San francisco 49ers 2025 schedule.
The 49ers face eight teams in 2025 that reached the postseason in 2023 (buffalo, dallas, detroit, green bay, kansas city, los angeles rams, miami and tampa bay) along. The san francisco 49ers are gearing up for the 2025 nfl season, set to kick off with a monday night football matchup against the new york jets.